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1

Molecular Design Strategies for Near-Infrared Ratiometric Fluorescent Probes Based on the Unique Spectral Properties of Aminocyanines

Kazuki Kiyose, Sakiko Aizawa, Eita Sasaki, Hirotatsu Kojima, Kenjiro Hanaoka, Takuya Terai, Yasuteru Urano, Tetsuo Nagano

Journal:

Chemistry - A European Journal

Année:

2009

Langue:

english

Fichier:

PDF, 404 KB

english, 2009

2

Nuclear cyclin B1 in human breast carcinoma as a potent prognostic factor

Takashi Suzuki, Tomohiro Urano, Yasuhiro Miki, Takuya Moriya, Jun-ichi Akahira, Takanori Ishida, Kuniko Horie, Satoshi Inoue, Hironobu Sasano

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 418 KB

english, 2007

3

Design and Synthesis of Highly Sensitive Fluorogenic Substrates for Glutathione S-Transferase and Application for Activity Imaging in Living Cells

Fujikawa, Yuuta, Urano, Yasuteru, Komatsu, Toru, Hanaoka, Kenjiro, Kojima, Hirotatsu, Terai, Takuya, Inoue, Hideshi, Nagano, Tetsuo

Journal:

Journal of the American Chemical Society

Année:

2008

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2008

4

Development of an Si-Rhodamine-Based Far-Red to Near-Infrared Fluorescence Probe Selective for Hypochlorous Acid and Its Applications for Biological Imaging

Koide, Yuichiro, Urano, Yasuteru, Hanaoka, Kenjiro, Terai, Takuya, Nagano, Tetsuo

Journal:

Journal of the American Chemical Society

Année:

2011

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2011

5

Development and Application of a Near-Infrared Fluorescence Probe for Oxidative Stress Based on Differential Reactivity of Linked Cyanine Dyes

Oushiki, Daihi, Kojima, Hirotatsu, Terai, Takuya, Arita, Makoto, Hanaoka, Kenjiro, Urano, Yasuteru, Nagano, Tetsuo

Journal:

Journal of the American Chemical Society

Année:

2010

Langue:

english

Fichier:

PDF, 3.48 MB

english, 2010

6

Palladium-Catalyzed Aromatic C−H Halogenation with Hydrogen Halides by Means of Electrochemical Oxidation

Kakiuchi, Fumitoshi, Kochi, Takuya, Mutsutani, Hitoshi, Kobayashi, Noboru, Urano, Seiya, Sato, Mitsuo, Nishiyama, Shigeru, Tanabe, Takamasa

Journal:

Journal of the American Chemical Society

Année:

2009

Langue:

english

Fichier:

PDF, 334 KB

english, 2009

7

Ruthenium-Catalyzed Amino- and Alkoxycarbonylations with Carbamoyl Chlorides and Alkyl Chloroformates via Aromatic C−H Bond Cleavage

Kochi, Takuya, Urano, Seiya, Seki, Hajime, Mizushima, Eiichiro, Sato, Mitsuo, Kakiuchi, Fumitoshi

Journal:

Journal of the American Chemical Society

Année:

2009

Langue:

english

Fichier:

PDF, 113 KB

english, 2009

8

Development of a series of near-infrared dark quenchers based on Si-rhodamines and their application to fluorescent probes

Myochin, Takuya, Hanaoka, Kenjiro, Iwaki, Shimpei, Ueno, Tasuku, Komatsu, Toru, Terai, Takuya, Nagano, Tetsuo, Urano, Yasuteru

Journal:

Journal of the American Chemical Society

Année:

2015

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2015

9

Design and Synthesis of a Highly Sensitive Off–On Fluorescent Chemosensor for Zinc Ions Utilizing Internal Charge Transfer

Kenjiro Hanaoka, Yasuaki Muramatsu, Yasuteru Urano, Takuya Terai, Tetsuo Nagano

Journal:

Chemistry - A European Journal

Année:

2010

Langue:

english

Fichier:

PDF, 328 KB

english, 2010

10

ChemInform Abstract: Ruthenium-Catalyzed Amino- and Alkoxycarbonylations with Carbamoyl Chlorides and Alkyl Chloroformates via Aromatic C—H Bond Cleavage.

Takuya Kochi, Seiya Urano, Hajime Seki, Eiichiro Mizushima, Mitsuo Sato, Fumitoshi Kakiuchi

Journal:

Année:

2009

Fichier:

PDF, 31 KB

2009

11

ChemInform Abstract: Palladium-Catalyzed Aromatic C—H Halogenation with Hydrogen Halides by Means of Electrochemical Oxidation.

Fumitoshi Kakiuchi, Takuya Kochi, Hitoshi Mutsutani, Noboru Kobayashi, Seiya Urano, Mitsuo Sato, Shigeru Nishiyama, Takamasa Tanabe

Journal:

Année:

2010

Fichier:

PDF, 46 KB

2010

12

Design and synthesis of a novel fluorescence probe for Zn2+ based on the spirolactam ring-opening process of rhodamine derivatives

Hiromi Sasaki, Kenjiro Hanaoka, Yasuteru Urano, Takuya Terai, Tetsuo Nagano

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2011

13

Epigenetic marks by DNA methylation specific to stem, germ and somatic cells in mice

Kunio Shiota, Yasushi Kogo, Jun Ohgane, Takuya Imamura, Atsushi Urano, Koichiro Nishino, Satoshi Tanaka, Naka Hattori

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 6.39 MB

english, 2002

14

Icariin improves memory impairment in Alzheimer's disease model mice (5xFAD) and attenuates amyloid β-induced neurite atrophy

Takuya Urano, Chihiro Tohda

Journal:

Phytotherapy Research

Année:

2010

Langue:

english

Fichier:

PDF, 650 KB

english, 2010

15

The Distribution of Several Elements in Cat Urine and the Relation Between the Content of Elements and Urolithiasis

Mariko Mochizuki, Misato Morikawa, Takuya Yogo, Kimiyo Urano, Katsumi Ishioka, Minoru Kishi, Ryo Hondo, Fukiko Ueda, Toshinori Sako, Fujiro Sakurai, Norio Yumoto, Masahiro Tagawa

Journal:

Biological Trace Element Research

Année:

2011

Langue:

english

Fichier:

PDF, 270 KB

english, 2011

16

DNA–RNA hybrid formation mediates RNAi-directed heterochromatin formation

Mina Nakama, Kei Kawakami, Takuya Kajitani, Takeshi Urano, Yota Murakami

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2012

17

Development of Luciferin Analogues Bearing an Amino Group and Their Application as BRET Donors

Hideo Takakura, Kiyoshi Sasakura, Tasuku Ueno, Yasuteru Urano, Takuya Terai, Kenjiro Hanaoka, Takashi Tsuboi, Tetsuo Nagano

Journal:

Chemistry – An Asian Journal

Année:

2010

Langue:

english

Fichier:

PDF, 311 KB

english, 2010

18

Aminoluciferins as Functional Bioluminogenic Substrates of Firefly Luciferase

Hideo Takakura, Ryosuke Kojima, Prof. Dr. Yasuteru Urano, Takuya Terai, Dr. Kenjiro Hanaoka, Prof. Dr. Tetsuo Nagano

Journal:

Chemistry – An Asian Journal

Année:

2011

Langue:

english

Fichier:

PDF, 832 KB

english, 2011

19

Contrast-enhanced US of ampullary carcinoma: correlations with pathological findings

Nobuyuki Kiura, Shozo Okamura, Fumihiro Urano, Kazuhiro Hiramatsu, Matsuyoshi Maeda, Takuya Ishikawa, Hidemi Goto, Yoshiki Hirooka

Journal:

Journal of Medical Ultrasonics

Année:

2012

Langue:

english

Fichier:

PDF, 557 KB

english, 2012

20

Arabidopsis stress-inducible gene for arginine decarboxylase AtADC2 is required for accumulation of putrescine in salt tolerance

Kaoru Urano, Yoshu Yoshiba, Tokihiko Nanjo, Takuya Ito, Kazuko Yamaguchi-Shinozaki, Kazuo Shinozaki

Journal:

Biochemical and Biophysical Research Communications

Année:

2004

Langue:

english

Fichier:

PDF, 247 KB

english, 2004

21

Desensitization of the inhibitory effect of norepinephrine on insulin secretion from pancreatic islets of exercise-trained rats

Yuriko Urano, Tomonobu Sakurai, Hiroshi Ueda, Junetsu Ogasawara, Takuya Sakurai, Megumi Takei, Tetsuya Izawa

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 373 KB

english, 2004

22

Memory enhancement by icariin in mice

Takuya Urano, Chihiro Tohda

Journal:

Neuroscience Research

Année:

2009

Langue:

english

Fichier:

PDF, 86 KB

english, 2009

23

Improvement of memory deficits by diosgenin in Alzheimer's disease model mice and the molecular mechanism underlying the effect

Takuya Urano, Chihiro Tohda

Journal:

Neuroscience Research

Année:

2010

Langue:

english

Fichier:

PDF, 70 KB

english, 2010

24

Elevation of plasma free PAI-1 levels as an integrated endothelial response to severe burns

Katsunori Aoki, Naoki Aikawa, Kazuhiko Sekine, Motoyasu Yamazaki, Takuya Mimura, Tetsumei Urano, Akikazu Takada

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 400 KB

english, 2001

25

Rational Design of Highly Sensitive Fluorescence Probes for Protease and Glycosidase Based on Precisely Controlled Spirocyclization

Sakabe, Masayo, Asanuma, Daisuke, Kamiya, Mako, Iwatate, Ryu J., Hanaoka, Kenjiro, Terai, Takuya, Nagano, Tetsuo, Urano, Yasuteru

Journal:

Journal of the American Chemical Society

Année:

2013

Langue:

english

Fichier:

PDF, 884 KB

english, 2013

26

Highly Activatable and Environment-Insensitive Optical Highlighters for Selective Spatiotemporal Imaging of Target Proteins

Kobayashi, Tomonori, Komatsu, Toru, Kamiya, Mako, Campos, Cláudia, González-Gaitán, Marcos, Terai, Takuya, Hanaoka, Kenjiro, Nagano, Tetsuo, Urano, Yasuteru

Journal:

Journal of the American Chemical Society

Année:

2012

Langue:

english

Fichier:

PDF, 2.75 MB

english, 2012

27

Development of NIR Fluorescent Dyes Based on Si–rhodamine for in Vivo Imaging

Koide, Yuichiro, Urano, Yasuteru, Hanaoka, Kenjiro, Piao, Wen, Kusakabe, Moriaki, Saito, Nae, Terai, Takuya, Okabe, Takayoshi, Nagano, Tetsuo

Journal:

Journal of the American Chemical Society

Année:

2012

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2012

28

Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced Electron Transfer and Its Application to a Long-Lived Protease Probe

Terai, Takuya, Kikuchi, Kazuya, Iwasawa, Shin-ya, Kawabe, Takao, Hirata, Yasunobu, Urano, Yasuteru, Nagano, Tetsuo

Journal:

Journal of the American Chemical Society

Année:

2006

Langue:

english

Fichier:

PDF, 235 KB

english, 2006

29

TokyoGreen derivatives as specific and practical fluorescent probes for UDP-glucuronosyltransferase (UGT) 1A1

Terai, Takuya, Tomiyasu, Rie, Ota, Tomoe, Ueno, Tasuku, Komatsu, Toru, Hanaoka, Kenjiro, Urano, Yasuteru, Nagano, Tetsuo

Journal:

Chemical Communications

Année:

2013

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2013

30

Effects of long-term low-dose oxygen supplementation on the epithelial function, collagen metabolism and interstitial fibrogenesis in the guinea pig lung

Takuya Aoki, Fumihiro Yamasawa, Takeo Kawashiro, Tetsuichi Shibata, Akitoshi Ishizaka, Tetsuya Urano, Yasumasa Okada

Journal:

Respiratory Research

Année:

2008

Langue:

english

Fichier:

PDF, 4.87 MB

english, 2008

31

A Simple and Effective Strategy To Increase the Sensitivity of Fluorescence Probes in Living Cells

Izumi, Saki, Urano, Yasuteru, Hanaoka, Kenjiro, Terai, Takuya, Nagano, Tetsuo

Journal:

Journal of the American Chemical Society

Année:

2009

Langue:

english

Fichier:

PDF, 462 KB

english, 2009

32

A Thiol-Reactive Fluorescence Probe Based on Donor-Excited Photoinduced Electron Transfer: Key Role of Ortho Substitution

Matsumoto, Takuya, Urano, Yasuteru, Shoda, Takuji, Kojima, Hirotatsu, Nagano, Tetsuo

Journal:

Organic Letters

Année:

2007

Langue:

english

Fichier:

PDF, 69 KB

english, 2007

33

Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced Electron Transfer and Its Application to a Long-Lived Protease Probe [ J. Am. Chem. Soc. 2006 , 128 , 6938−6946].

Terai, Takuya, Kikuchi, Kazuya, Iwasawa, Shin-ya, Kawabe, Takao, Hirata, Yasunobu, Urano, Yasuteru, Nagano, Tetsuo

Journal:

Journal of the American Chemical Society

Année:

2006

Langue:

english

Fichier:

PDF, 21 KB

english, 2006

34

A practical strategy to create near-infrared luminescent probes: conversion from fluorescein-based sensors

Terai, Takuya, Urano, Yasuteru, Izumi, Saki, Kojima, Hirotatsu, Nagano, Tetsuo

Journal:

Chemical Communications

Année:

2012

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2012

35

Sensitive Detection of Acrolein in Serum Using Time-Resolved Luminescence

Togashi, Masataka, Urano, Yasuteru, Kojima, Hirotatsu, Terai, Takuya, Hanaoka, Kenjiro, Igarashi, Kazuei, Hirata, Yasunobu, Nagano, Tetsuo

Journal:

Organic Letters

Année:

2010

Langue:

english

Fichier:

PDF, 205 KB

english, 2010

36

Structure of conjugated polyketone reductase fromCandida parapsilosisIFO 0708 reveals conformational changes for substrate recognition upon NADPH binding

Qin, Hui-Min, Yamamura, Akihiro, Miyakawa, Takuya, Kataoka, Michihiko, Nagai, Takahiro, Kitamura, Nahoko, Urano, Nobuyuki, Maruoka, Shintaro, Ohtsuka, Jun, Nagata, Koji, Shimizu, Sakayu, Tanokura, Mas

Journal:

Applied Microbiology and Biotechnology

Année:

2014

Langue:

english

Fichier:

PDF, 449 KB

english, 2014

37

Development of a Highly Sensitive Fluorescence Probe for Hydrogen Peroxide

Abo, Masahiro, Urano, Yasuteru, Hanaoka, Kenjiro, Terai, Takuya, Komatsu, Toru, Nagano, Tetsuo

Journal:

Journal of the American Chemical Society

Année:

2011

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2011

38

Structural basis for high substrate-binding affinity and enantioselectivity of 3-quinuclidinone reductase AtQR

Hou, Feng, Miyakawa, Takuya, Kataoka, Michihiko, Takeshita, Daijiro, Kumashiro, Shoko, Uzura, Atsuko, Urano, Nobuyuki, Nagata, Koji, Shimizu, Sakayu, Tanokura, Masaru

Journal:

Biochemical and Biophysical Research Communications

Année:

2014

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2014

39

TRIM27/MRTF-B-Dependent Integrin β1 Expression Defines Leading Cells in Cancer Cell Collectives

Kato, Takuya, Enomoto, Atsushi, Watanabe, Takashi, Haga, Hisashi, Ishida, Sumire, Kondo, Yuji, Furukawa, Koichi, Urano, Takeshi, Mii, Shinji, Weng, Liang, Ishida-Takagishi, Maki, Asai, Masato, Asai, N

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 3.83 MB

english, 2014

40

Design and Development of Enzymatically Activatable Photosensitizer Based on Unique Characteristics of Thiazole Orange

Koide, Yuichiro, Urano, Yasuteru, Yatsushige, Akira, Hanaoka, Kenjiro, Terai, Takuya, Nagano, Tetsuo

Journal:

Journal of the American Chemical Society

Année:

2009

Langue:

english

Fichier:

PDF, 2.33 MB

english, 2009

41

Evolution of Group 14 Rhodamines as Platforms for Near-Infrared Fluorescence Probes Utilizing Photoinduced Electron Transfer

Koide, Yuichiro, Urano, Yasuteru, Hanaoka, Kenjiro, Terai, Takuya, Nagano, Tetsuo

Journal:

ACS Chemical Biology

Année:

2011

Langue:

english

Fichier:

PDF, 4.07 MB

english, 2011

42

A long-lived luminescent probe to sensitively detect arylamine N-acetyltransferase (NAT) activity of cells

Terai, Takuya, Kikuchi, Kazuya, Urano, Yasuteru, Kojima, Hirotatsu, Nagano, Tetsuo

Journal:

Chemical Communications

Année:

2012

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2012

43

Boron Dipyrromethene As a Fluorescent Caging Group for Single-Photon Uncaging with Long-Wavelength Visible Light

Umeda, Nobuhiro, Takahashi, Hironori, Kamiya, Mako, Ueno, Tasuku, Komatsu, Toru, Terai, Takuya, Hanaoka, Kenjiro, Nagano, Tetsuo, Urano, Yasuteru

Journal:

ACS Chemical Biology

Année:

2014

Langue:

english

Fichier:

PDF, 2.35 MB

english, 2014

44

In Situ Evaluation of Kinetic Resolution Catalysts for Nitroaldol by Rationally Designed Fluorescence Probe

Matsumoto, Takuya, Urano, Yasuteru, Takahashi, Yoshinori, Mori, Yusuke, Terai, Takuya, Nagano, Tetsuo

Journal:

Journal of Organic Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.62 MB

english, 2011

45

Development of 2,6-carboxy-substituted boron dipyrromethene (BODIPY) as a novel scaffold of ratiometric fluorescent probes for live cell imaging

Komatsu, Toru, Urano, Yasuteru, Fujikawa, Yuuta, Kobayashi, Tomonori, Kojima, Hirotatsu, Terai, Takuya, Hanaoka, Kenjiro, Nagano, Tetsuo

Journal:

Chemical Communications

Année:

2009

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2009

46

Rational design of boron dipyrromethene (BODIPY)-based photobleaching-resistant fluorophores applicable to a protein dynamics study

Komatsu, Toru, Oushiki, Daihi, Takeda, Aoi, Miyamura, Masaki, Ueno, Tasuku, Terai, Takuya, Hanaoka, Kenjiro, Urano, Yasuteru, Mineno, Tomoko, Nagano, Tetsuo

Journal:

Chemical Communications

Année:

2011

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2011

47

Fluorometric assay of integrin activity with a small-molecular probe that senses the binding site microenvironment

Komatsu, Toru, Takeda, Aoi, Hanaoka, Kenjiro, Terai, Takuya, Ueno, Tasuku, Tada, Yukio, Nagano, Tetsuo, Urano, Yasuteru

Journal:

Chemical Communications

Année:

2014

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2014

48

A reversible near-infrared fluorescence probe for reactive oxygen species based on Te–rhodamine

Koide, Yuichiro, Kawaguchi, Mitsuyasu, Urano, Yasuteru, Hanaoka, Kenjiro, Komatsu, Toru, Abo, Masahiro, Terai, Takuya, Nagano, Tetsuo

Journal:

Chemical Communications

Année:

2012

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2012

49

Selective Ablation of β-Galactosidase-Expressing Cells with a Rationally Designed Activatable Photosensitizer

Ichikawa, Yuki, Kamiya, Mako, Obata, Fumiaki, Miura, Masayuki, Terai, Takuya, Komatsu, Toru, Ueno, Tasuku, Hanaoka, Kenjiro, Nagano, Tetsuo, Urano, Yasuteru

Journal:

Angewandte Chemie

Année:

2014

Langue:

english

Fichier:

PDF, 922 KB

english, 2014

50

Selective Ablation of β-Galactosidase-Expressing Cells with a Rationally Designed Activatable Photosensitizer

Ichikawa, Yuki, Kamiya, Mako, Obata, Fumiaki, Miura, Masayuki, Terai, Takuya, Komatsu, Toru, Ueno, Tasuku, Hanaoka, Kenjiro, Nagano, Tetsuo, Urano, Yasuteru

Journal:

Angewandte Chemie International Edition

Année:

2014

Langue:

english

Fichier:

PDF, 930 KB

english, 2014